Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.5
Substance Class Protein
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
3184JGF2SO
Record Status Validated (UNII)
Record Version
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Name Type Language Details References
DEMUPITAMAB
Domain Jurisdiction Naming Organization
drug  
INN  
Official Name
English  
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS EGFR (EPIDERMAL GROWTH FACTOR RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB)), HOMO SAPIENS MONOCLONAL ANTIBODY
Common Name
English  
N63AB
Common Name
English  
DEMUPITAMAB [INN]
Common Name
English  
IMMUNOGLOBULIN IGG1, ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR) (HUMAN MONOCLONAL N63AB .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL N63AB .KAPPA.-CHAIN, DIMER
Common Name
English  
Code System Code Type Description References
CAS
2249926-74-5
Created by admin on Thu Mar 26 00:52:53 EDT 2020 , Edited by admin on Thu Mar 26 00:52:53 EDT 2020
PRIMARY
INN
11211
Created by admin on Thu Mar 26 00:52:53 EDT 2020 , Edited by admin on Thu Mar 26 00:52:53 EDT 2020
PRIMARY
From To
1_22 1_97
2_22 2_97
2_146 2_202
2_222 4_214
2_263 2_323
1_146 1_202
2_369 2_427
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_222 3_214
1_228 2_228
1_231 2_231
1_263 1_323
1_369 1_427
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_299
N 2_299
Related Record Type Details References
INNOVATOR->PARENT
none
Mediator Substance Details
none
Created by admin on Thu Mar 26 00:52:53 EDT 2020 , Edited by admin on Thu Mar 26 00:52:53 EDT 2020
TARGET -> INHIBITOR
none
Mediator Substance Details
none
Created by admin on Thu Mar 26 00:52:53 EDT 2020 , Edited by admin on Thu Mar 26 00:52:53 EDT 2020
Structural Modifications
Modification Type Location Site Location Type Residue Modified Extent Modification Name Modification ID
AMINO_ACID_SUBSTITUTION [1_1] [2_1] N-TERMINUS PIDOLIC ACID SZB83O1W42
AMINO ACID REMOVAL [1_449] [2_449] C-TERMINUS LYSINE K3Z4F929H6
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL 0
Note References
[Validation]WARNING:There are 2 substances with a similar sequence to subunit [3,4]:
(Perform similarity search on subunit [3])
found approximate duplicate (97%) sequence in Subunit [3] of "DT958C4NWR" ("CUDAROLIMAB")
found approximate duplicate (97%) sequence in Subunit [4] of "DT958C4NWR" ("CUDAROLIMAB")
Created Thu Mar 26 00:52:53 EDT 2020
Created By admin
Last Edited Thu Mar 26 00:52:53 EDT 2020
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File
1 STN STN (SCIFINDER)
2 P122 INN PUBLIC_DOMAIN_RELEASE
3 GSRS System-generated Validation messages VALIDATION_MESSAGE Thu Mar 26 00:52:53 EDT 2020
4 GSRS System-generated Validation messages VALIDATION_MESSAGE Thu Mar 26 00:52:53 EDT 2020
5 MABS, 2019, VOL. 11, NO. 1, 145€“152 JA
6 INN 122 INN