Basic Searches
Searches without any special characters (listed below) will return items that contain the exact value(s) entered in the search field. This means that searching for "ASPIRIN CALCIUM" won't return any items that have "ASPIRIN GLYCINE CALCIUM" because the search term doesn't match exactly.
Boolean Operators
OR - searches with terms separated by " OR " will return items that contain any of the terms in the search.
Example: "ASPIRIN" OR "CALCIUM" will return items that have strings like "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because they contain at least one of the terms in the search.

AND - searches with terms separated by " AND " will return items that contain all the terms in the search.
Example: "ASPIRIN" AND "CALCIUM" won't return items that have strings "ASPIRIN GLYCINE" and "GLYCINE CALCIUM" because neither contain both terms, but it will return "ASPIRIN GLYCINE CALCIUM" because it contains both search terms.
version 2.5
Substance Class Protein
Protein Type MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type IGG1
Sequence Origin CHIMERIC/HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
17C83BVV62
Record Status Validated (UNII)
Record Version
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Name Type Language Details References
LOSATUXIZUMAB VEDOTIN
Domain Jurisdiction Naming Organization
drug  
INN  
INN  
Official Name
English  
ABBV 221 [WHO-DD]
Common Name
English  
LOSATUXIZUMAB VEDOTIN [INN]
Common Name
English  
ABBV-221
Common Name
English  
Classification Tree Code System Code References
NCI_THESAURUS C2167
Created by admin on Thu Mar 26 00:26:43 EDT 2020 , Edited by admin on Thu Mar 26 00:26:43 EDT 2020
Code System Code Type Description References
INN
10342
Created by admin on Thu Mar 26 00:26:43 EDT 2020 , Edited by admin on Thu Mar 26 00:26:43 EDT 2020
PRIMARY
CAS
1685249-67-5
Created by admin on Thu Mar 26 00:26:43 EDT 2020 , Edited by admin on Thu Mar 26 00:26:43 EDT 2020
PRIMARY
From To
1_22 1_96
1_143 1_199
1_219 3_214
1_225 2_225
1_228 2_228
1_260 1_320
1_366 1_424
2_22 2_96
2_143 2_199
2_219 4_214
2_260 2_320
2_366 2_424
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_296
N 2_296
Related Record Type Details References
CONJUGATE COMPONENT->CONJUGATE
none
Mediator Substance Details
none
Created by admin on Thu Mar 26 00:26:43 EDT 2020 , Edited by admin on Thu Mar 26 00:26:43 EDT 2020
TARGET->CONJUGATED TOXIN
none
Mediator Substance Details
none
Created by admin on Thu Mar 26 00:26:43 EDT 2020 , Edited by admin on Thu Mar 26 00:26:43 EDT 2020
CONJUGATE COMPONENT->CONJUGATE
none
none
Mediator Substance Details
none
Created by admin on Thu Mar 26 00:26:43 EDT 2020 , Edited by admin on Thu Mar 26 00:26:43 EDT 2020
Related Record Type Details References
ACTIVE MOIETY
none
none
Mediator Substance Details
none
Created by admin on Thu Mar 26 00:26:43 EDT 2020 , Edited by admin on Thu Mar 26 00:26:43 EDT 2020
Agent Modifications
Modification Process Modification Role Modification Type Amount Modification Agent Approved ID
TOXIN CONJUGATION SGD-1006 026S2O80A8
Structural Modifications
Modification Type Location Site Location Type Residue Modified Extent Modification Name Modification ID
SUBSTITUTION [1_219] [1_225] [1_228] [2_219] [2_225] [2_228] [3_214] [4_214] C
Amount:
CYSTEINE-VC-MMAE 6603L01WUR
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:CALCULATED CHEMICAL 0
Note References
[Validation]WARNING:Calculated weight [144900.80] is greater than 5% off of given weight [154000.00]
Created Thu Mar 26 00:26:43 EDT 2020
Created By admin
Last Edited Thu Mar 26 00:26:43 EDT 2020
Last Edited By admin
Index Source Text / Citation Source Type Tags Date Accessed File
1 SRS import [17C83BVV62] SRS NOMEN Fri Apr 28 15:06:18 EDT 2017
2 GSRS System-generated Validation messages VALIDATION_MESSAGE Thu Mar 26 00:26:40 EDT 2020
3 adis insight WEBSITE PUBLIC_DOMAIN_RELEASE NOMEN
4 GSRS System-generated Validation messages VALIDATION_MESSAGE Thu Mar 26 00:26:40 EDT 2020
5 stn STN (SCIFINDER) NOMEN PUBLIC_DOMAIN_RELEASE
6 https://adisinsight.springer.com/drugs/800042094 WEB PAGE
7 WHO-DD WHO DRUG DICTIONARY PUBLIC_DOMAIN_RELEASE NOMEN
8 INN SRS NOMEN PUBLIC_DOMAIN_RELEASE AUTO_SELECTED
9 https://www.adcreview.com/drugmap/losatuxizumab-vedotin-abbv-221/ WEB PAGE
10 LOSATUXIZUMAB VEDOTIN [INN] SRS_LOCATOR
11 SYSTEM
12 STN STN (SCIFINDER)
13 review WEBSITE NOMEN PUBLIC_DOMAIN_RELEASE
14 SRS CODE IMPORT SRS NOMEN Fri Apr 28 15:06:18 EDT 2017